Tyamara is receiving treatment at Edenvale Hospital for stomach TB and a liver condition.
It has also been reported that the talented artist is now on life support and breathing through oxygen machines.
His manager Anele Hlazo appealed to his fans and supporters to offer prayers for Tyamara as his condition has taken a turn for the worse.
According to close sources, the ailing singer is not speaking at all and some of his vital organs including his liver have stopped working.
Another source said: “We just pray for a miracle. Otherwise, his situation is bad”.
Tyamara is one of South Africa’s most celebrated gospel singers. His hit single “Mphefumlo Wam” turned him into a household name.